Hippocrates in 400 or so BC wrote about a study of patients who had what he called karkinos or crab.  The present day word is Κάβουρας pronounced Kávouras.  What he described in these patients was advanced cancer.  No one knows why he called it Crab, but that doesn’t limit the imagination of medical historians. 

It could be the pain often felt in cancer patients being severe and persistent like the pain felt on the pinch of a crab’s claw inspired the name.  It could be because cancers are often hard like the shell of a crab.  My own theory is that like crabs which slowly nibble away at dead animals, gradually rendering it unrecognizable and eventually only a skeleton, cancer eats away at the host until the patient looks cadaverous.

Celsus, in the first century AD wrote a medical encyclopedia which he termed Cancer, the Latin equivalent of Karkinos.  Cancer became the English term for malignant tumors, and karkinos survived in the term for malignant tumors arising from the ectoderm; carcinomas.

For thirty years I worked primarily as what is termed a surgical pathologist.  That doesn’t mean I did surgery.  It means that I looked at tissues and organs removed from patients, documenting all sorts of things like size, color, texture and shape, confirming what clinicians already suspected, documenting what had been removed, and expanding the knowledge of the nature of a patient’s disease process and its expected behavior.  We made what we termed a pathological diagnosis.  A clinical suspicion of tuberculosis can be confirmed and antibiotic sensitivities performed by culture, but that may take a month because the tubercle bacillus grows very slowly.  A biopsy with appropriate stains can confirm tuberculosis in a couple of days, and the clinician can put the patient on medications that will probably work with a change in medications when the sensitivities are done, if that is necessary.

The type of residency that I did, took five years.  I’m sure that many things in the process have changed since the 1970s, but I spent a year doing autopsies.  I performed or assisted on over 400 during my training, most of them done during the first year.  I have no idea how many surgical specimens I looked at.  I sat at a microscope looking at cases at the same time the staff pathologist did, listening to him (they were all men) discuss what he saw, and identifying those changes and cataloguing them in my mind. 

The last two years were spent in the laboratory learning the methodology of all of the tests done, looking at other methods, the equipment used, equipment required for other methods of doing the analyses, and discussing everything with the two pathologists mainly involved in the laboratory.

Make no mistake; all of the tests were done by technicians and technologists.  Our job was to understand the process well enough that when quality control drifted, or a test just stopped working we could troubleshoot the process and help fix it.

Our relationship with technologists was testy at times.  Most were very bright, knew they knew more about actually doing the test than we did, and many resented the fact that we made more money, and saw us as a hindrance to their own advancement.  Over the years I worked closely with some, particularly as the pathologist responsible for the transfusion service, and very little with others.  Careful observation showed some to be perfectly capable of solo flight, and I only got involved in their business when there was a need.  Other techs and supervisors wanted a co-pilot.

So, I started off talking about crabs.  What has all of this got to do with cancer?

Perhaps the most critical diagnoses I made were diagnoses of cancer.  Over a thirty year career I missed a few – that I know about – and I remember all of them…acutely….painfully.

One was a tiny biopsy of skin received in 1979 or ‘80 that proved to be Merkel Cell Carcinoma.  There was no excuse.  I was the only pathologist reading microscopic slides that day and I had a full load.  I called the process Basal Cell Carcinoma.  A year later I got a call from an academic institution where the patient was being seen asking me to review the slides.  I had that sick, sinking feeling as soon as I stuck the slide under the microscope.

In the spring of 2015 I developed a small, soft nodule on my lower leg.  It grew over the next several months and I asked my primary care doctor to look at it.  He thought it was nothing.  A couple of months later I asked the dermatologist to look at it.  His remark was, “Whatever it is it’s benign.”  It was soft, not fixed to surrounding tissues, tender, and except for the rate of growth it showed no signs usually associated with malignancy.

Finally, in September I decided to get the thing taken off because it was becoming unsightly.  Everybody was shocked when the diagnosis of Merkel Cell Carcinoma came back.

My first thought was, “I’m going to die of this and I deserve it.”

Merkel Cell Carcinoma is rare.  It is usually seen in fair skinned people (check), in highly sun-exposed areas (no check), has a bluish hue of the overlying skin (check), is frequently missed (check), and has a fifty-four percent five year survival rate provided it has not already spread at the time of diagnosis, in which case the survival rate becomes about 34%.

In recent years it has come to light that 80% of people with the tumor have a polyoma virus called the Merkel Cell virus that is involved in the process of becoming malignant.  The mode of transmission of the virus is obscure.  I probably have the virus considering the fact that the other inciting factor is UV light exposure.  Older individuals and those who are immunosuppressed are more prone to develop the tumor.

In October of 2015 I had the biopsy.  In December I had the site widely excised with a skin graft.  I did well, but it was still mid-January before I was fully active.  In September of 2016 the tumor recurred near my previous surgical site.

I’ve been examined with multiple CT scans, MRIs and a PET scan and at present there is no evidence of spread beyond the area on my leg.  Consultation with my surgeon and a Radiation Oncologist at Duke has led me to choose radiation therapy to my leg.  The other option is amputation which I’m not keen on.  Radiation therapy is not innocuous.  There are short and long term side effects, one of which is developing another malignancy in the irradiated area.  However, if I don’t have radiation I won’t have to worry about a future malignancy.

I'm also taking Turkey Tail mushroom.  Four studies of patients with different kinds of cancer have shown that adding Turkey Tail to radiation, surgery or chemotherapy improves survival.  It's pretty cheap and painless.  It has also been a part of Chinese traditional medicine for about a thousand years.

i tried Essiac Tea.  It tastes like a swamp smells, and an attempt to study its effect on cancer was stopped when it became clear that the manufacturer was not cooperating with the study.  So, that looks like all down side to me.  I would never abandon proven treatment for alternative therapy, but I'm OK with combining traditional medicine with scientific medicine. 

I’ll be staying in Caring House, a low-cost residence for cancer patients with access to a shuttle to take me back and forth for daily treatments.  I should come out on the other side of this sometime just before Christmas.

The treatments only take a couple of hours a day – mostly setup time – and The Caring House is a nice place with wifi, so you may still hear from me while I’m there.

I’m always realistic but optimistic.  I won’t bother you with more details unless you ask for them.

In less than a week this awful presidential campaign will be over.  I’m optimistic.

Live long and prosper.




Views: 249

Comment by Sheila Reep on November 2, 2016 at 2:59pm

I am all for anything that works. Heck, we don't know everything. Good luck!!

Comment by Ron Powell on November 2, 2016 at 3:09pm

Cancer, the crab,  is a constellation.

Cancer, the crab, is also one of the twelve signs of the Zodiac.

I have no clue as to why and how the astronomers and astrologers of antiquity decided on the names of what they saw in their, night sky, but the names have come down through the ages with all sorts of meaning and values attached and associated with them.

Perhaps you can delve into the matter more deeply  while you're  on your recuperative holiday....

Be well....

Comment by koshersalaami on November 2, 2016 at 3:23pm

If you send any mail, buy these:


Live long and prosper

Zei gezunt (Yiddish for Be Well)

Comment by Zanelle on November 2, 2016 at 4:17pm

I want the details.  I want to know what the facility is like and the ride on the shuttle.  I want to know who the other people around you are and how the staff is and if there is any infighting.  I want to know how you feel and I want to rejoice with you when you come out in December.   What an ordeal.  Best wishes and big hug.

Comment by nerd cred on November 2, 2016 at 5:45pm

You too, live long and prosper. And what Zanelle said. All that.

Comment by Rosigami on November 2, 2016 at 5:52pm

I am hoping you don't ascribe anything past coincidence to your developing a cancer like the one you didn't catch all those years ago.

I admire both your optimism and your willingness to try alternative therapies in addition to your other treatment.

I hope you will continue to update us on your experiences as you go through this. I care.

When will you start your radiation treatments?

Comment by alsoknownas on November 2, 2016 at 6:07pm

Jeez Rodney.

 Just get well, ok?

Comment by Zanelle on November 2, 2016 at 6:40pm

See I like to make connections like you did with the stars and crabs and time and space.  it seems there is more going on than we know.  Networks and cosmic paths in and out of suffering and being alive.  I think the energy paths probably exist after death too.  Those pictures Ron posted are cosmic and deep.  Beauty.  Glad you are in OUR network, R.  Hugs

Comment by Rodney Roe on November 2, 2016 at 7:28pm

Rosigami, I start the 7th. I think that I will keep a wen log as blogs originally were of the process. I have friends and family who can read and keep up. They can read and keep abreast, I appreciate your concern. Really.

Zanelle, I will share the juicy stuff, too ;-) i am very impressed with the facility and all of the staff so far.

kosh, that must be the same gezunt in the blessing when you sneeze: gezuntheit.

everyone, thanks.

Comment by Rodney Roe on November 3, 2016 at 7:19am

Steel Breeze, thanks. I'll do that.

Ron Powell, I didn't comment on your two images. Like most of the constellations, I find the image of a crab in Cancer a stretch. But, the stars looked different a few thousand years ago, so maybe it was more obvious.
As far as the Zodiac is concerned, I was born on the cusp of Scorpio and Sagittarius, so I could never figure out what was supposed to happen to the on any given day and I discounted it from the beginning. My daughter says I can't figure out what it means without finding out where my moon was at the hour I was born, or some similar nonsense. I like the image, though.


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